La. Olopoenia et al., EIKENELLA-CORRODENS ENDOCARDITIS IN AN INTRAVENOUS-DRUG-USER - CASE-REPORT AND LITERATURE-REVIEW, Journal of the National Medical Association, 86(4), 1994, pp. 313-315
A rare case of Eikenella corrodens endocarditis in an intravenous drug
user is reported. Repeated blood cultures from the patient establishe
d the diagnosis of this infection. However, evaluation of the cardiac
function using two-dimensional echocardiography with Doppler flow demo
nstrated a large pedunculated tricuspid vegetation. Also evident on th
is study was a dilated right ventricle with diminished contractility a
nd regurgitation. Complete sterilization of the blood was achieved aft
er a 2-week course of intravenous penicillin and gentamicin followed b
y an additional 4-week course of intravenous penicillin alone. Clinici
ans treating suspected IV drug users should be aware of the potential
pathogenicity of this rare, facultative, anaerobic gram-negative bacil
lus (E corrodens). A combination of intravenous penicillin and aminogl
ycoside should be considered as the initial treatment followed by an a
dditional course of intravenous penicillin for such patients with valv
ular vegetation.