Canada's health care system is challenged by a crisis of affordability
. A sluggish economy and substantial federal, provincial, and territor
ial debt have caused health care spending, in spite of a good record o
f cost control, to consume nearly 10% of Canada's gross domestic produ
ct, largely due to a denominator effect. Issues identified as warranti
ng further investigation as potential approaches to further reducing c
ost in order to match available resources include therapeutic effectiv
eness, drug use, hospital utilization, manpower planning, consumer acc
ess, and population approaches to improving health status. An importan
t role exists for clinical investigators to contribute to health care
reform.