SPECTROSCOPIC STUDIES ON CYANOCUPRATE-CATALYZED 3-COMPONENT COUPLINGS- UNDERSTANDING THE CATALYTIC CYCLE

Authors
LIPSHUTZ BH WOOD MR
Citation
Bh. Lipshutz et Mr. Wood, SPECTROSCOPIC STUDIES ON CYANOCUPRATE-CATALYZED 3-COMPONENT COUPLINGS- UNDERSTANDING THE CATALYTIC CYCLE, Tetrahedron letters, 35(35), 1994, pp. 6433-6436
Citations number
6
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
35
Issue
35
Year of publication
1994
Pages
6433 - 6436
Database
ISI
SICI code
0040-4039(1994)35:35<6433:SSOC3C>2.0.ZU;2-#
Abstract
Low temperature 1H NMR analysis of a reaction mixture containing a vin ylic zirconocene, MeLi, Me(3)ZnLi, 20 mol % Me(2)Cu(CN)Li-2 and an eno ne, reagents which together lead to the Michael delivery of a vinyl li gand, reveals the presence of a zinc enolate, the species likely to be responsible for the subsequent alkylation or aldol reaction as the fi nal step in 3-component couplings.