APPLICATION OF N,S-CHELATING CHIRAL ZINC BIS(ARENETHIOLATE) COMPLEXESAS NEW PRECURSOR CATALYSTS IN THE ENANTIOSELECTIVE ADDITION OF DIETHYLZINC TO ALDEHYDES

Authors
RIJNBERG E JASTRZEBSKI JTBH JANSSEN MD BOERSMA J VANKOTEN G
Citation
E. Rijnberg et al., APPLICATION OF N,S-CHELATING CHIRAL ZINC BIS(ARENETHIOLATE) COMPLEXESAS NEW PRECURSOR CATALYSTS IN THE ENANTIOSELECTIVE ADDITION OF DIETHYLZINC TO ALDEHYDES, Tetrahedron letters, 35(35), 1994, pp. 6521-6524
Citations number
15
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
35
Issue
35
Year of publication
1994
Pages
6521 - 6524
Database
ISI
SICI code
0040-4039(1994)35:35<6521:AONCZB>2.0.ZU;2-5
Abstract
The addition of diethylzinc to aldehydes in the presence of a catalyti c amount of enantiomerically pure N,S-chelated {2-[(R)-1-(dimethylamin o)ethyl]phenylthiolato}zinc afforded the corresponding secondary alcoh ols in neatly quantitative yields with optical purities of up to 99 % e.e. under mild reaction conditions.