SPECIFIC IGE TO INHALANT ALLERGENS IN SWE AT OF PATIENTS WITH ATOPIC-DERMATITIS

Authors
JUNG K LADWIG K SCHLENVOIGT G HERRMANN D MOTHS C LINSE R NEUMANN C
Citation
K. Jung et al., SPECIFIC IGE TO INHALANT ALLERGENS IN SWE AT OF PATIENTS WITH ATOPIC-DERMATITIS, Allergologie, 17(8), 1994, pp. 361-364
Citations number
NO
Categorie Soggetti
Allergy
Journal title
Allergologie → ACNP
ISSN journal
03445062
Volume
17
Issue
8
Year of publication
1994
Pages
361 - 364
Database
ISI
SICI code
0344-5062(1994)17:8<361:SITIAI>2.0.ZU;2-K
Abstract
Sweating has been discussed as a pathogenetic factor in atopic dermati tis. Here we show, that IgE which is specifically directed against all ergens and which is also found in the serum of the same individuals ca n be detected in significant amounts in the sweat. It is suggested, th at excretion of specific IgE with the sweat of patients with atopic de rmatitis may lead to enhanced binding to Langerhans cells and other Ig E-receptor-positive cells, facilitating antigen trapping in atopic ski n.