Deep neck-space infections may cause potentially life-threatening comp
lications of head and neck infections. Lateral pharyngeal space infect
ions in particular predispose to development of suppurative jugular ve
in thrombosis, which may be associated with anaerobic bacteremia and s
eptic pulmonary emboli (Lemierre's syndrome). We describe a case of Le
mierre's syndrome, a very rare entity in the antibiotic era, complicat
ing mastoiditis. Surgical debridement and drainage in conjunction with
antibiotic therapy resulted in prompt improvement in the patient's co
ndition.