Kn. Malizos et al., OSTEONECROSIS OF THE FEMORAL-HEAD IN IMMUNOSUPPRESSED PATIENTS - HIP SALVAGING WITH IMPLANTATION OF A VASCULARIZED FIBULAR GRAFT, Microsurgery, 15(7), 1994, pp. 485-491
Osteonecrosis frequently occurs in patients being treated with steroid
s for conditions such as systemic lupus erythematosus and other collag
en diseases and in renal transplant recipients. It remains an unsolved
problem and can cause more disability than the underlying disease, pa
rticularly in young patients. In a series of eight young patients who
received continuous corticosteroids and immunosuppressive agents, we a
ttempted hip salvage in ten joints by implantation of a vascularised f
ibular graft into the necrotic femoral head. Follow-up ranged from 18
to 36 months. Joints which were operated on prior to articular surface
collapse had complete restoration of normal function. In patients wit
h more advanced lesions, surgery resulted in a painless hip, improved
range of motion, and cessation of further progress of the disease. The
preliminary data are considered encouraging enough to suggest that th
e vascularised fibular graft is an appropriate method for hip salvage
in immunosuppressed patients with osteonecrosis of the femoral head. (
C) 1994 Wiley-Liss, Inc.