Two cases of neurological dysfunction are presented. Neurological defi
cits after recovery from anaesthesia are unusual in young women periop
eratively. In the first case, a 39-yr-old woman presented at 36-wk ges
tation with antepartum haemorrhage and in labour Pregnancy had been co
mplicated by pre-eclampsia and she underwent emergency Caesarean secti
on under general anaesthesia without complication. The trachea was ext
ubated when she was awake but almost immediately she became hypertensi
ve, obtunded and reintubation was required. Her pupils became fixed an
d dilated but the Computerised Axial Tomogram (CT) was normal A coagul
opathy was evident. She made a full neurological recovery within 24 hr
. On the same day, a previously healthy 41-yr-old woman who had underg
one uneventful surgery for uterine prolapse 24 hr previously developed
headache, nausea and over the next four hours signs of progressive br
ainstem ischaemia. The CT scan showed oedema of the mid- and hindbrain
. Brainstem death was confirmed 12 hr later and the post-mortem reveal
ed acute dissection of the vertebral artery secondary to cystic medial
necrosis. Such dramatic neurological sequelae are rare but the import
ance of identifying ''at risk'' groups is underlined as is early recog
nition of neurological injury postoperatively.