NMDA REDOX SITE MODULATES LONG-TERM POTENTIATION OF NMDA BUT NOT OF AMPA RECEPTORS

Authors
GOZLAN H CHINESTRA P DIABIRA D BENARI Y
Citation
H. Gozlan et al., NMDA REDOX SITE MODULATES LONG-TERM POTENTIATION OF NMDA BUT NOT OF AMPA RECEPTORS, European journal of pharmacology, 262(1-2), 1994, pp. 180000003-180000004
Citations number
6
Categorie Soggetti
Pharmacology & Pharmacy
Journal title
European journal of pharmacology → ACNP
ISSN journal
00142999
Volume
262
Issue
1-2
Year of publication
1994
Pages
180000003 - 180000004
Database
ISI
SICI code
0014-2999(1994)262:1-2<180000003:NRSMLP>2.0.ZU;2-F
Abstract
We have compared the effects of redox drugs on long-term potentiation mediated by AMPA or NMDA receptors. A reducing and an oxidizing agent had no effect on long-term potentiation mediated by AMPA receptors. In contrast, the induction of long-term potentiation mediated by NMDA re ceptors was prevented by a thiol oxidizing drug and restored by a disu lfide reducing agent.