IRIDIUM(I) AND PHASE-TRANSFER-CATALYZED HYDROGEN-TRANSFER REDUCTION OF KETONES USING POTASSIUM FLUORIDE ON ALUMINA AS A BASE

Authors
GOLDBERG Y ALPER H
Citation
Y. Goldberg et H. Alper, IRIDIUM(I) AND PHASE-TRANSFER-CATALYZED HYDROGEN-TRANSFER REDUCTION OF KETONES USING POTASSIUM FLUORIDE ON ALUMINA AS A BASE, Journal of molecular catalysis, 92(2), 1994, pp. 149-153
Citations number
25
Categorie Soggetti
Chemistry Physical
Journal title
Journal of molecular catalysis → ACNP
ISSN journal
03045102
Volume
92
Issue
2
Year of publication
1994
Pages
149 - 153
Database
ISI
SICI code
0304-5102(1994)92:2<149:IAPHRO>2.0.ZU;2-Y
Abstract
The hydrogen transfer reduction of alkyl aryl (heteroaryl) ketones rea dily occurs at 82-degrees-C in a solid-liquid biphasic system when usi ng 2-propanol as hydrogen donor, potassium fluoride on alumina (50 wt. %) as a base, [ Ir(COD)Cl]2 as the metal catalyst and 18-crown-6 as th e phase-transfer agent. The molar ratio of ketone : [Ir] : F-] : 18-cr own-6 was 200 : 1 : 5 : 2. A number of alkyl aryl, and alkyl heteroary l carbinols have been prepared in 73-84% isolated yield under HTR-PTC conditions.