IS THE ACRAL-LENTIGINOUS MELANOMA (ALM) M ORE MALIGNANT THAN THE SUPERFICIAL SPREADING MELANOMA (SSM) IN A HIGH-RISK LOCATION - A MATCHED-PAIR COMPARISON OF 113 EACH ALM AND SSM IN A MULTICENTER STUDY
H. Breuninger et al., IS THE ACRAL-LENTIGINOUS MELANOMA (ALM) M ORE MALIGNANT THAN THE SUPERFICIAL SPREADING MELANOMA (SSM) IN A HIGH-RISK LOCATION - A MATCHED-PAIR COMPARISON OF 113 EACH ALM AND SSM IN A MULTICENTER STUDY, Hautarzt, 45(8), 1994, pp. 529-531
Even today, the prognosis of acrallentiginous melanoma (ALM) remains a
controversial topic. We present a large case study including all know
n factors relevant for prognosis. 113 ALMs in 3616 melanoma patients w
ere paired as precisely as possible with their twins, i.e. with 113 su
perficial spreading melanomas (SSM) from a group of 619 SSMs with high
-risk location. The ALMs and SSMs were equivalent in tumor thickness,
patient gender and mode of treatment. The follow-up period was for at
least 5 years. The 5-year Kaplan-Meier survival curve in both groups a
re identical. The poor prognosis often ascribed to ALM results from th
e prognostic factor location. ALM should therefore be regarded as acra
l localized melanoma.