RECURRENT RESPIRATORY PAPILLOMATOSIS - THE MANCHESTER EXPERIENCE, 1974-1992

A series of 59 patients of all ages with recurrent respiratory papillo matosis (RRP) treated over an 18-year period is presented. A number of these patients were initially diagnosed in childhood but required tre atment throughout adult life. The frequency of laser treatment was not related to either disease duration or age at onset. In 28 patients, t he HPV type was identified, showing that HPV type 11 was more common i n children and ran a more protracted clinical course. The requirement for tracheostomy in this series was small, whereas the incidence of ma lignant change in adult patients was significant.