PCR TYPING OF THE LOCUS D17S30 (YNZ22 VNTR) IN AN ITALIAN POPULATION-SAMPLE

A sample of 202 subjects living in 2 Italian provinces (Ancona and Par ma) was tested for YNZ22 polymorphism by the polymerase chain reaction (PCR). After amplification, the phenotypes were separated by agarose gel electrophoresis, stained with ethidium bromide and identified by c omparison with a molecular weight marker. No heterogeneity was found b etween the 2 populations. Alleles, pooled in 4 groups to calculate the Hardy-Weinberg (H-W) equilibrium, showed good accordance between obse rved and expected values. The power of discrimination (PD) was 0.95 an d the chance of exclusion was 0.69. The allele comparison with previou s studies on Caucasians showed no significant difference.