AN EFFICIENT SYNTHESIS OF DIMETHOXY-4-QUINOLONES AND TRIMETHOXY-4-QUINOLONES

Authors
TODA J FUSE T KISHIKAWA E ANDO N NEGISHI R HORIGUCHI Y SANO T
Citation
J. Toda et al., AN EFFICIENT SYNTHESIS OF DIMETHOXY-4-QUINOLONES AND TRIMETHOXY-4-QUINOLONES, Heterocycles, 38(9), 1994, pp. 2091-2097
Citations number
8
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Heterocycles → ACNP
ISSN journal
03855414
Volume
38
Issue
9
Year of publication
1994
Pages
2091 - 2097
Database
ISI
SICI code
0385-5414(1994)38:9<2091:AESODA>2.0.ZU;2-8
Abstract
An excellent method of preparation of N-aryl-enamino esters (4) was ac hieved by developing N-N exchange reaction of an N-methyl-enamino este r (6) with di- and trimethoxyanilines (3). Thermolysis of 4 in xylene gave di- and trimethoxy-4-quinolones (7) in excellent yields.