COMPLEX-FORMATION OF HUMAN ALPHA-1-ANTITRYPSIN WITH COMPONENTS IN SCHISTOSOMA-MANSONI CERCARIAE

Authors
MODHA J DOENHOFF MJ
Citation
J. Modha et Mj. Doenhoff, COMPLEX-FORMATION OF HUMAN ALPHA-1-ANTITRYPSIN WITH COMPONENTS IN SCHISTOSOMA-MANSONI CERCARIAE, Parasite immunology, 16(8), 1994, pp. 447-450
Citations number
34
Categorie Soggetti
Immunology,Parasitiology
Journal title
Parasite immunology → ACNP
ISSN journal
01419838
Volume
16
Issue
8
Year of publication
1994
Pages
447 - 450
Database
ISI
SICI code
0141-9838(1994)16:8<447:COHAWC>2.0.ZU;2-B
Abstract
Human alpha-1-antitrypsin (alpha 1-AT) was incubated with an extract o f Schistosoma mansoni cercariae or porcine pancreatic elastase and ana lysed by immunoelectrophoresis and Western blotting. The inhibitor was shown to form complexes with components in S. mansoni cercariae in th e same way as elastase. The role of alpha 1-AT in S. mansoni infection is discussed.