Ml. Druzin et E. Stier, MATERNAL PLATELET COUNT AT DELIVERY IN PATIENTS WITH IDIOPATHIC THROMBOCYTOPENIC PURPURA, NOT RELATED TO PERIOPERATIVE COMPLICATIONS, Journal of the American College of Surgeons, 179(3), 1994, pp. 264-266
BACKGROUND: The relationship between maternal platelet count at the ti
me of cesarean section and perioperative and postpartum operative comp
lications was examined. STUDY DESIGN: A retrospective analysis of 46 p
regnancies in 41 women with histories of idiopathic thrombocytopenic p
urpura was performed. Thirty-five patients had platelet counts greater
than 100,000 before delivery and 11 had counts less than 100,000. Sta
tistical comparisons were made using Student's t test and chi-square t
est. RESULTS: The perioperative and postpartum course for patients in
the two groups differed significantly only in platelet counts at deliv
ery. Change in hematocrit (from admission to postpartum), estimated bl
ood loss at cesarean section, incidence of wound complications or tran
sfusion, were not significantly different. There were no neonatal comp
lications. CONCLUSIONS: Mild thrombocytopenia in patients with idiopat
hic thrombocytopenic purpura is unlikely to be associated with an incr
ease in blood loss, infection, wound complication, or need for transfu
sion.