EFFICIENT SYNTHESIS OF NEW 5-SUBSTITUTED URACIL NUCLEOSIDES USEFUL FOR LINKER ARM INCORPORATION

5-Substituted uracil nucleosides useful for the attachment of linker a rms to nucleic acids are prepared from arabinoaminooxazoline and dimet hyl alpha-bromomethylfumarate in a short reaction sequence without usi ng any protecting groups, and incorporated into oligodeoxyribonucleoti de.