THE 5Q- SYNDROME - A SCIENTIFIC AND CLINICAL UPDATE

Authors
TEFFERI A MATHEW P NOEL P
Citation
A. Tefferi et al., THE 5Q- SYNDROME - A SCIENTIFIC AND CLINICAL UPDATE, Leukemia & lymphoma, 14(5-6), 1994, pp. 375-378
Citations number
NO
Categorie Soggetti
Hematology
Journal title
Leukemia & lymphoma → ACNP
ISSN journal
10428194
Volume
14
Issue
5-6
Year of publication
1994
Pages
375 - 378
Database
ISI
SICI code
1042-8194(1994)14:5-6<375:T5S-AS>2.0.ZU;2-1
Abstract
The 5q- syndrome is a subset of the myelodysplastic syndromes characte rized by hypolobulated micromegakaryocytic hyperplasia and an intersti tial deletion of the long arm of chromosome 5. In this concise review, we discuss the current understanding in regard to the genetic basis o f the disorder and provide an updated clinical report on 43 patients w ith the disease who were seen at our institution.