INFLUENCE OF PINEALECTOMY OF THE CIRCADIA N LOCOMOTOR RHYTHM OF RATS AND ITS SENSITIVITY TO THE HYPNOTIC DRUGS

Authors
ARUSHANIAN EB ORHII BP
Citation
Eb. Arushanian et Bp. Orhii, INFLUENCE OF PINEALECTOMY OF THE CIRCADIA N LOCOMOTOR RHYTHM OF RATS AND ITS SENSITIVITY TO THE HYPNOTIC DRUGS, Zurnal vyssej nervnoj deatelnosti im. I.P. Pavlova, 44(1), 1994, pp. 143-148
Citations number
14
Categorie Soggetti
Physiology,Neurosciences
Journal title
Zurnal vyssej nervnoj deatelnosti im. I.P. Pavlova → ACNP
ISSN journal
00444677
Volume
44
Issue
1
Year of publication
1994
Pages
143 - 148
Database
ISI
SICI code
0044-4677(1994)44:1<143:IOPOTC>2.0.ZU;2-2
Abstract
In the paper were studied the rats' individual circadian locomotor act ivity rhythm patterns and their day and night time sensitivity to hexo barbital sodium and diazepam. Pinealectomy without altering the rhythm patterns significantly increased their amplitude and enhanced the hyp notic effect of hexobarbital both in the daytime and at night and that of diazepam only in the daytime. The animal rhythm patterns and the c ircadian variations of their sensitivity to the hypnotic drugs were su ggested to depend on the individual variations of the pineal activity.