Sp. Gregory et Pe. Holt, THE IMMEDIATE EFFECT OF COLPOSUSPENSION ON RESTING AND STRESSED URETHRAL PRESSURE PROFILES IN ANESTHETIZED INCONTINENT BITCHES, Veterinary surgery, 23(5), 1994, pp. 330-340
The aim of this study was to document what changes in the resting and
stressed urethral pressure profile occur in the incontinent bitch with
urethral sphincter mechanism incompetence (SMI) immediately after col
posuspension. Resting and stressed subtracted simultaneous urethral pr
essure profilometry was performed immediately pre- and postcolposuspen
sion in 26 bitches diagnosed with SMI. All of the urethral pressure pr
ofiles were measured in anaesthetized bitches using a standard techniq
ue and two orientations of the catheter transducers (dorsal and left).
Readable pre- and postoperative urethral pressure profiles were obtai
ned in 20 of the 26 bitches. Subjective and objective evaluation of th
e profiles showed significant differences in the profiles pre- and pos
tcolposuspension. Immediately postoperatively there were significant (
P < .05) increases in functional profile length, maximum urethral clos
ure pressure (MUCP), and distance between the bladder neck and the fir
st negative respiratory peak and stressed spike. There was a significa
nt (P < .001) decrease in the percentage of negative spikes extending
below the resting intravesical pressure on the subtracted profile. The
pressure transmission profiles were significantly (P < .001) altered
by surgery. The findings presented support the hypothesis that colposu
spension may restore continence by increasing pressure transmission to
the proximal urethra and bladder neck. The results also suggest that
immediately after surgery functional urethral length and urethral resi
stance are increased. (C) Copyright 1994 by The American College of Ve
terinary Surgeons