ROOM-TEMPERATURE STABLE PERFLUOROCARBON EMULSIONS WITH ACCEPTABLE HALF-LIVES IN THE RETICULOENDOTHELIAL SYSTEM

Authors
WEERS JG LIU J FIELDS T RESCH P CAVIN J ARLAUSKAS RA
Citation
Jg. Weers et al., ROOM-TEMPERATURE STABLE PERFLUOROCARBON EMULSIONS WITH ACCEPTABLE HALF-LIVES IN THE RETICULOENDOTHELIAL SYSTEM, Artificial cells, blood substitutes, and immobilization biotechnology, 22(4), 1994, pp. 1175-1182
Citations number
7
Categorie Soggetti
Engineering, Biomedical","Materials Science, Biomaterials
Journal title
Artificial cells, blood substitutes, and immobilization biotechnology → ACNP
ISSN journal
10731199
Volume
22
Issue
4
Year of publication
1994
Pages
1175 - 1182
Database
ISI
SICI code
1073-1199(1994)22:4<1175:RSPEWA>2.0.ZU;2-X
Abstract
Prolonged room temperature stability (i.e. zero particle growth) can b e achieved for concentrated emulsions of perflubron (perfluorooctyl br omide) or perfluorodecalin via addition of a secondary high molecular weight, lipophilic fluorocarbon component. Due to their enhanced lipop hilic character, the secondary fluorocarbon components have acceptable half-lives in the organs of the reticuloendothelial system.