Jg. Weers et al., ROOM-TEMPERATURE STABLE PERFLUOROCARBON EMULSIONS WITH ACCEPTABLE HALF-LIVES IN THE RETICULOENDOTHELIAL SYSTEM, Artificial cells, blood substitutes, and immobilization biotechnology, 22(4), 1994, pp. 1175-1182
Prolonged room temperature stability (i.e. zero particle growth) can b
e achieved for concentrated emulsions of perflubron (perfluorooctyl br
omide) or perfluorodecalin via addition of a secondary high molecular
weight, lipophilic fluorocarbon component. Due to their enhanced lipop
hilic character, the secondary fluorocarbon components have acceptable
half-lives in the organs of the reticuloendothelial system.