ANTIBIOTIC-RESISTANCE AND PENICILLIN TOLERANCE IN CLINICAL ISOLATES OF GROUP-B STREPTOCOCCI

Authors
BETRIU C GOMEZ M SANCHEZ A CRUCEYRA A ROMERO J PICAZO JJ
Citation
C. Betriu et al., ANTIBIOTIC-RESISTANCE AND PENICILLIN TOLERANCE IN CLINICAL ISOLATES OF GROUP-B STREPTOCOCCI, Antimicrobial agents and chemotherapy, 38(9), 1994, pp. 2183-2186
Citations number
39
Categorie Soggetti
Pharmacology & Pharmacy",Microbiology
Journal title
Antimicrobial agents and chemotherapy → ACNP
ISSN journal
00664804
Volume
38
Issue
9
Year of publication
1994
Pages
2183 - 2186
Database
ISI
SICI code
0066-4804(1994)38:9<2183:AAPTIC>2.0.ZU;2-W
Abstract
The aim of this study was to determine the susceptibility patterns of 100 group B streptococcal strains isolated in our hospital and to asce rtain tolerance to penicillin by determining quantitative killing curv es. We found two strains with intermediate susceptibility to penicilli n and eight strains to ampicillin. Seventeen isolates were tolerant to penicillin, with bacterial counts decreasing 2 to 3 log during the fi rst 8 h but stilt above 10(2) CFU/ml after 24 h. The kinetic study sho ws that penicillin tolerance is not rare among group B streptococci is olated in our hospital.