A seven-year-old, male, intact samoyed with chronic diarrhoea was diag
nosed as having a regional granulomatous enterocolitis confined primar
ily to the distal ileum and caecum. Radiographic and histopathological
findings revealed that the most severe inflammatory changes involved
the caecum. Long-term corticosteroid management, a short course of met
ronidazole, and a three-month period of treatment with azathioprine fa
iled to adequately control the diarrhoea. Surgical resection of the ca
ecum eventually helped resolve the condition.