CUTANEOUS INVOLVEMENT IN CHRONIC MYELOMONOCYTIC LEUKEMIA

Background. Chronic myelomonocytic leukemia has been associated with v arious nonspecific cutaneous manifestations. Rarely has the leukemia b een reported to directly affect the skin. Methods. This case documents the progression of a patient who ultimately developed chronic myelomo nocytic leukemia, by clinical examination, hematologic parameters, der matopathology, and bone marrow pathology. Results, The skin showed non specific cutaneous involvement, progressing to specific leukemic lesio ns parallel with increasing systemic and hematologic involvement. Conc lusions. Chronic myelomonocytic leukemia can manifest with lesions of leukemia cutis. The possibility of nonspecific cutaneous involvement i n the preleukemic phase exists.