THE ROLE OF HOST FACTORS IN MEASLES-VIRUS PERSISTENCE

Authors
SCHNEIDERSCHAULIES S SCHNORR JJ DUNSTER LM SCHNEIDERSCHAULIES J TERMEULEN V
Citation
S. Schneiderschaulies et al., THE ROLE OF HOST FACTORS IN MEASLES-VIRUS PERSISTENCE, Seminars in virology, 5(4), 1994, pp. 273-280
Citations number
75
Categorie Soggetti
Virology
Journal title
Seminars in virology → ACNP
ISSN journal
10445773
Volume
5
Issue
4
Year of publication
1994
Pages
273 - 280
Database
ISI
SICI code
1044-5773(1994)5:4<273:TROHFI>2.0.ZU;2-7
Abstract
As critical steps in the life cycle of measles virus (MV), the efficie ncy of uptake into and replication in susceptible host cells are gover ned by cellular determinants. Measles virus infections of cells of the human CNS are characterized by particular constraints imposed on vira l transcription and translation attenuating viral gene functions and t hus contributing to the pathogenesis of MV persistence in these cells.