SYNTHESIS OF 14-BETA,17-BETA-PROPANOESTRADIOLS VIA INTRAMOLECULAR CYCLIZATIONS

Authors
BULL JR MOUNTFORD PG
Citation
Jr. Bull et Pg. Mountford, SYNTHESIS OF 14-BETA,17-BETA-PROPANOESTRADIOLS VIA INTRAMOLECULAR CYCLIZATIONS, Synlett, (9), 1994, pp. 711-712
Citations number
8
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synlett → ACNP
ISSN journal
09365214
Issue
9
Year of publication
1994
Pages
711 - 712
Database
ISI
SICI code
0936-5214(1994):9<711:SO1VIC>2.0.ZU;2-9
Abstract
llyl-3-methoxy-14beta-estra-1,3,5(10)-trien-17-one is converted regios electively into the 14beta-acetonyl 17-ketone or the 14beta-formylethy l 17-ketone, which undergo intramolecular aldol condensation or reduct ive cyclisation respectively, leading to 14beta,17beta-propano analogu es of estradiol.