K. Dendene et al., KINETICS OF LACTOSE ISOMERIZATION TO LACTULOSE IN AN ALKALINE-MEDIUM, Journal of chemical technology and biotechnology, 61(1), 1994, pp. 37-42
The aim of this work was to determine easily and quickly the operating
conditions for the industrial production of lactulose (rate of isomer
isation, rate of lactose degradation, reaction time, temperature, pH).
The kinetic equations of lactulose formation and lactose degradation
in an alkaline medium (NaOH) were determined. Experiments were carried
out at different OH- concentrations (0.5 x 10(-2)-19 x 10(-2) mol dm-
3) and at different temperatures (328-353 K). A kinetic model is prese
nted which can be used to describe the experimental results and hence
a procedure for industrial production.