STABILITY OF A MINERAL MEMBRANE ULTRAFILTRATION REACTOR FOR PEPTIC HYDROLYSIS OF HEMOGLOBIN

Authors
SANNIER F PIOT JM DHULSTER P GUILLOCHON D
Citation
F. Sannier et al., STABILITY OF A MINERAL MEMBRANE ULTRAFILTRATION REACTOR FOR PEPTIC HYDROLYSIS OF HEMOGLOBIN, Journal of chemical technology and biotechnology, 61(1), 1994, pp. 43-47
Citations number
9
Categorie Soggetti
Engineering, Chemical",Chemistry,"Biothechnology & Applied Migrobiology
Journal title
Journal of chemical technology and biotechnology → ACNP
ISSN journal
02682575
Volume
61
Issue
1
Year of publication
1994
Pages
43 - 47
Database
ISI
SICI code
0268-2575(1994)61:1<43:SOAMMU>2.0.ZU;2-8
Abstract
Factors involved in the activity decay of an ultrafiltration reactor d uring the hydrolysis of hemoglobin by pepsin were studied. Biochemical and hydrodynamic parameters were assessed. The product of hydrolysis showed no inhibitory effect. Autolysis and mechanical damage of pepsin were limited by the presence of hemoglobin. Activity decay was mainly a result of the leakage of pepsin through the membrane. Electrostatic charges carried by either hemoglobin or pepsin were involved in the p ermeation process.