Rm. Szeimies et al., SUCCESSFUL TREATMENT OF HYDROXYETHYL STARCH-INDUCED PRURITUS WITH TOPICAL CAPSAICIN, British journal of dermatology, 131(3), 1994, pp. 380-382
We report a case of recalcitrant pruritus after infusion therapy with
hydroxyethyl starch (HES) for sudden deafness. The diagnosis was confi
rmed by detection of typical HES storage vacuoles within dermal macrop
hages and perineural cells. Treatment with antihistamines and antiprur
itic agents, UVB irradiation, and neuroleptic drugs, was ineffective.
Topical capsaicin (0.05%) twice daily produced excellent symptomatic r
elief, without side-effects.