INDIVIDUAL BOVINE-SPECIFIC AND SPECIES-SPECIFIC AUTOGENOUS VACCINE INTREATMENT OF BOVINE CUTANEOUS PAPILLOMATOSIS

Bovine cutaneous papillomatosis, a viral infection, causes benign grow th from the dermis. Conventional treatment involves vaccination using a species-specific autogenous vaccine. There was regression of the pap illomas in the naturally infected calves after vaccination with specie s-specific autogenous vaccine 4 months later in one farm. A complete r egression of the warts occurred with individual bovine-specific autoge nous vaccine. This could he due to the presence of antigenic variants immunologically distinct from the parent virus. thus requiring the nee d to use wan samples from each individual affected calf to prepare the individual bovine specific autogenous vaccine. These field variants w ill greatly complicate the treatment and the management of this diseas e due to the enormous work involved in the production of individual bo vine-specific autogenous vaccine.