CHIRAL AND PHASE-TRANSFER AGENTS .8. SYNTHESIS OF 2 CHIRAL MONOAZA-18-CROWN-6 ETHERS FROM 1,3-2,4-DI-O-ETHYLIDENE-D-GLUCITOL AND PYRIDINE-2,6-DIMETHANOL
Ea. Elperina et al., CHIRAL AND PHASE-TRANSFER AGENTS .8. SYNTHESIS OF 2 CHIRAL MONOAZA-18-CROWN-6 ETHERS FROM 1,3-2,4-DI-O-ETHYLIDENE-D-GLUCITOL AND PYRIDINE-2,6-DIMETHANOL, Russian chemical bulletin, 42(4), 1993, pp. 751-754
Starting from 1,3:2,4-di-O-ethylidene-D-glucitol (1), two regioisomeri
c monoaza-18-crown-6 ethers with C2 symmetry were synthesized. A simpl
e route was suggested for the preparation of a diol that is a convenie
nt intermediate for the synthesis of chiral aza-crown ethers from diol
1.