Je. Maher et al., FETAL ECHOCARDIOGRAPHY IN GRAVIDAS WITH HISTORIC RISK-FACTORS FOR CONGENITAL HEART-DISEASE, American journal of perinatology, 11(5), 1994, pp. 334-336
All fetal echocardiograms performed at our institution between January
1, 1986, and June 1, 1991, were reviewed. The echocardiogram referral
indication and results were verified for all women studied. Historic
risk factors under consideration were pregestational diabetes, anticon
vulsant or lithium ingestion in the first trimester, and a family hist
ory of congenital heart disease. Women with historic risk factors who
had either a fetal abnormality on antenatal sonography or a known aneu
ploid fetus prior to the fetal echocardiograph were excluded. Of the 9
94 women who had a fetal echocardiogram performed during this study pe
riod, 486 (48.9%) were evaluated solely on the basis of a historic ris
k factor. Four of the 486 women (0.8%) were diagnosed as having a sign
ificant fetal structural cardiac malformation. Two of the four fetuses
succumbed to obstetric complications. The remaining two infants were
delivered at term and are doing well after postnatal cardiac surgery.
In this select group of women with risk factors but no recognized feta
l abnormality, the incidence of significant cardiac lesions was low. A
lthough indications for fetal echocardiography must be evaluated on an
individual basis, our data do not support a recommendation for the ro
utine use of fetal echocardiography as a screening test in all women w
ith historic risk factors.