African horsesickness (AHS) is a very serious, non-contagious disease
of horses and other solipeds caused by an arthropod-borne orbivirus of
the family Reoviridae. The epizootic nature of the disease makes rapi
d, accurate diagnosis of AHS absolutely essential. Currently, diagnosi
s of AHS is based on typical clinical signs and lesions, a history con
sistent with vector transmission and confirmation by laboratory detect
ion of virus and/or anti-AHS virus antibodies. The clinicopathologic p
resentation of AHS, current and next generation laboratory diagnostic
methods are discussed.