NEUROMUSCULAR BLOCKADE IN THE MANAGEMENT OF CEREBRAL-PALSY

Neuromuscular blocking agents-45% alcohol, 4% to 6% aqueous phenol, lo cal anesthetics, and botulinum A toxin-have been used for many years i n the evaluation and management of spasticity and movement disorders i n children with cerebral palsy. Recent reports suggest that longer-act ing neuromuscular blocking agents may impact positively on the natural history of dynamic deformity and improve health-related quality of Li fe. This review includes the mechanism of action, techniques, indicati ons, complications, and clinical outcomes associated with these agents .