Sh. Bailine et al., FLUMAZENIL REVERSAL OF BENZODIAZEPINE-INDUCED SEDATION FOR A PATIENT WITH SEVERE PRE-ECT ANXIETY, Convulsive therapy, 10(1), 1994, pp. 65-68
We describe various measures to reduce severe anxiety that interfered
with much-needed maintenance electroconvulsive therapy in a 32-year-ol
d man. Treatment with ketamine met with moderate success, and then lar
ge doses of lorazepam and midazalam were used. The potential anticonvu
lsant effect of these drugs was successfully reversed by the administr
ation of intravenous flumazenil just prior to the treatments.