Rmma. Nuyts et al., TREATMENT OF HYPOTONOUS MACULOPATHY AFTER TRABECULECTOMY WITH MITOMYCIN-C, American journal of ophthalmology, 118(3), 1994, pp. 322-331
We treated 34 eyes of 32 patients who developed a hypotonous maculopat
hy after a trabeculectomy with mitomycin C with various treatment stra
tegies. Placement of a Megasoft Bandage Contact Lens in 24 eyes did no
t result in a notable increase in intraocular pressure or visual acuit
y. Intrableb injection of autologous blood in 22 eyes resulted in a me
an +/- standard deviation (S.D.) increase in intraocular pressure from
4.3 +/- 1.8 mm Hg before injection to 8.6 +/- 4.6 mm Hg after injecti
on. Mean logMAR visual acuity improved from 0.71 +/- 0.40 to 0.32 +/-
0.25. After a surgical revision of 16 eyes, intraocular pressure incre
ased from 4.1 +/- 1.9 mm Hg to 11.3 +/- 4.0 mm Hg, and logMAR visual a
cuity improved from 0.61 +/- 0.30 to 0.22 +/- 0.24. At the last follow
-up examination (12.2 +/- 5.1 months after the trabeculectomy), 31 eye
s (91.2%) had an intraocular pressure greater than 6 mm Hg. Hypotonous
maculopathy after trabeculectomy with mitomycin C can be treated succ
essfully by autologous blood injection and surgical revision of the fi
ltration site.