TUBERCULOSIS - CURRENT ISSUES IN DIAGNOSIS AND TREATMENT

The incidence of tuberculosis began to decline in 1801, which was prob ably due to improving socioeconomic conditions (certainly not the effo rts of the medical profession). Patients cannot be treated unless they are detected, which underlines the importance of notification and cas e finding. Full multiagent chemotherapy is necessary to give the best chance of permanent cure and to prevent the emergence of resistance; c ompliance with treatment is increased by making it readily accessible and increasing the degree of supervision. With the resurgence of inter est in tuberculosis since the rising incidence of the late 1980s a rev iew of the state of diagnosis and treatment is due. This one covers so me areas of current interest: the role of vaccination, chemoprophylaxi s, tuberculosis and HIV, new methods of diagnosis, drug resistance and alternative approaches to treatment.