Aj. Evans et al., SCREENING-DETECTED AND SYMPTOMATIC DUCTAL CARCINOMA IN-SITU - MAMMOGRAPHIC FEATURES WITH PATHOLOGICAL CORRELATION, Radiology, 191(1), 1994, pp. 237-240
PURPOSE: To compare the mammographic and pathologic features of screen
ing-detected and symptomatic ductal carcinoma in situ (DCIS). MATERIAL
S AND METHODS: The mammographic and pathologic features of 54 screenin
g-detected and 77 symptomatic cases of DCIS were compared. Patients we
re aged 30-76 years (mean, 58 years). RESULTS: Diffuse involvement was
seen in 10 patients (13%) with symptoms but in none of the screening-
detected group (P < .05). The disease was radiologically more extensiv
e in the symptomatic group. Calcifications in the symptomatic group (n
= 48) were less likely to have a ductal distribution than those in th
e screening-detected group (n = 48) (30 [63%] vs 40 [83%], respectivel
y; P < .05). At histologic examination in some cases, the symptomatic
group (n = 76) included eight (11%) patients with cribriform-micropapi
llary, large-cell tumors (P < .05) and less comedocarcinoma (20 [26%]
vs 23 [45%], respectively; P < .05) compared with the screening-detect
ed group (n = 51). CONCLUSION. The results show differences in the rad
iologic and pathologic features of screening-detected and symptomatic
DCIS.