Dw. Vane et al., SPINAL-ANESTHESIA FOR PRIMARY REPAIR OF GASTROSCHISIS - A NEW AND SAFE TECHNIQUE FOR SELECTED PATIENTS, Journal of pediatric surgery, 29(9), 1994, pp. 1234-1235
Spinal anesthesia has been described for infants and premature babies
undergoing minor operative procedures. The advantages of shorter opera
ting time, avoidance of intubation, and shorter hospital stay have mad
e this the gold standard for premature and other high-risk infants req
uiring minor procedures. However, little is known about this technique
for major interventions in newborns and preterm infants. Recently, fo
ur infants born with gastroschisis underwent repair under spinal anest
hesia. Two had accompanying intestinal atresia (one with a prenatal pe
rforation and pan-hypopituitarism), and two had intact gastrointestina
l systems. The gestational ages were 39, 33, 36, and 36 weeks, respect
ively. All had primary closure of the defect; one had no repair of the
atresia because the bowel was thick and matted with a significant pee
l, and the defect was not identified. In the second case with atresia,
necrosis and perforation of a localized segment of intestine was iden
tified proximal to the intestinal atresia, and was exteriorized with t
he primary repair. When they arrived in the operating room, all four i
nfants were breathing spontaneously, on room air, after appropriate fl
uid resuscitation. All underwent spinal anesthesia, which was the only
agent used for the operation. The operative time was 45, 25, 30, and
25 minutes, respectively (mean, 31.25 minutes). The duration of anesth
esia was 170 to 230 minutes (mean. 205 minutes). All infants were retu
rned to the neonatal intensive care unit on room air and breathing spo
ntaneously. One was given morphine postoperatively and suffered signif
icant respiratory depression, requiring intubation. It appears that sp
inal anesthesia is safe and effective for major operative procedures i
n high-risk infants. This mechanism often alleviates the need for intu
bation and the concomitant risks for premature babies undergoing opera
tion who demonstrate no need for assisted ventilation preoperatively.
Given the proven efficacy and safety of this technique, modern neonata
l care obligates the consideration of spinal anesthesia for major and
minor operative procedures in selected patients. Copyright (C) 1994 by
W.B. Saunders Company