TOXICITY STUDIES OF PARTIALLY HYDROLYZED GUAR GUM

Authors
TAKAHASHI H YANG SI FUJIKI M KIM M YAMAMOTO T GREENBERG NA
Citation
H. Takahashi et al., TOXICITY STUDIES OF PARTIALLY HYDROLYZED GUAR GUM, Journal of the American College of Toxicology, 13(4), 1994, pp. 273-278
Citations number
12
Categorie Soggetti
Pharmacology & Pharmacy",Toxicology
Journal title
Journal of the American College of Toxicology → ACNP
ISSN journal
07300913
Volume
13
Issue
4
Year of publication
1994
Pages
273 - 278
Database
ISI
SICI code
0730-0913(1994)13:4<273:TSOPHG>2.0.ZU;2-Y
Abstract
The toxicity of partially hydrolyzed guar gum (PHGG, average molecular weight 20,000) was evaluated in a 28-day, repeated oral dosing study (gavage) in rats at doses of 0, 500, and 2,500 mg/kg/day and in Salmon ella typhimurium, with and without metabolic activation. PHGG did not elicit any signs of toxicity at the doses tested. PHGG was not mutagen ic.