A DIMERIC (PHENYLSULFONYL)OXAZOLIDINE

Authors
HIRSCHLER J BERGER B BOLTE M
Citation
J. Hirschler et al., A DIMERIC (PHENYLSULFONYL)OXAZOLIDINE, Acta crystallographica. Section C, Crystal structure communications, 50, 1994, pp. 1279-1281
Citations number
7
Categorie Soggetti
Crystallography
Journal title
Acta crystallographica. Section C, Crystal structure communications → ACNP
ISSN journal
01082701
Volume
50
Year of publication
1994
Part
8
Pages
1279 - 1281
Database
ISI
SICI code
0108-2701(1994)50:<1279:AD(>2.0.ZU;2-A
Abstract
We report the crystal structure of ,3-oxazolidin-2-yl]-5-{2-(1R,2S)-[( 2R,4R,5R)-3-(p- idin-2-yl]-1-hydroxycyclopentyl}-1-cyclopentanone, C42 H44Cl2N2O(8)S(2) (1). The chlorophenyl-sulfonyl substituent is cis to the phenyl ring on each oxazolidine heterocycle. Each chlorophenyl-sul fonyl substituent adopts a folded conformation by which the aromatic r ing shields the heterocycle. The oxazolidine rings have envelope confo rmations with C(3) and O(17) out of their respective planes. An intra- molecular exists between the hydroxyl group O(11) and the ketone O(7) [O(11)...O(7) 2.840 Angstrom, O(11)-H(11)...O(7) 134.0 degrees].