CYCLIZATION DICHOTOMY OF ESTERS OF 3-UREIDO-2-CYANO-2-PROPENOIC AND 3-UREIDO-2-ACYL-2-PROPENOIC ACIDS

Authors
LEDVINA M FARKAS J
Citation
M. Ledvina et J. Farkas, CYCLIZATION DICHOTOMY OF ESTERS OF 3-UREIDO-2-CYANO-2-PROPENOIC AND 3-UREIDO-2-ACYL-2-PROPENOIC ACIDS, Collection of Czechoslovak Chemical Communications, 59(8), 1994, pp. 1841-1852
Citations number
20
Categorie Soggetti
Chemistry
Journal title
Collection of Czechoslovak Chemical Communications → ACNP
ISSN journal
00100765
Volume
59
Issue
8
Year of publication
1994
Pages
1841 - 1852
Database
ISI
SICI code
0010-0765(1994)59:8<1841:CDOEO3>2.0.ZU;2-4
Abstract
The preparation of E and Z isomers of 3-ureido-2-cyano-2-propenoates I a - Id and their base-catalyzed isomerization and cyclization to 5-car boxycytosine derivatives IIa - IIf and 5-cyanouracil derivatives IIIa and IIIb is described. Also described is the preparation of 3-ureido-2 -acyl-2-propenoates Va - Vd and their base-catalyzed cyclization to 5- carboxy-2(1H)-pyrimidone derivatives VIa - VIc and 5-acyluracils VIIa - VIIc.