The notion that social and psychological processes may influence somat
ic illness is not new and not a product of our time. Already Aristotel
es expressed his awareness of the need for social and mental well-bein
g for the prospects of a long healthy life. With the progress of natur
al sciences, however, with new revolutionary discoveries, like that of
bacteria, antibiotics, insuline, etc., reductionism was also introduc
ed into the research process. An unfortunate consequence was the lack
of overview, the failure to see links between various research fields,
between various research paradigms and between various research tradi
tions. Whereas the Ancient Greeks were intuitively positive that body
and mind constantly influence each other, scientists of the last centu
ry have promoted the view that bodily functions can be objectively stu
died, but that the functions of the mind are best captured by beliefs
and religion. However, thanks to interactive initiatives from such,,ha
rd'' discipline as neurobiology, physiology, neuroendocrinology with m
ore,,soft ware'' disciplines like psychology, psychiatry, sociology, l
earning sciences etc., we are beginning to adopt an entirely new persp
ective on disease processes. This development has become possible beca
use the need for interaction between scientists of various disciplines
became so obvious. This led to the development of new research method
ology, which combined elements from various,,soft'' and,,hard'' discip
lines. The methods to examine stress reactivity is one example. A ment
al stressor is standardized in a laboratory setting and bodily respons
es are objectively assessed. This methodology enables us to investigat
e to what extent an individual is inclined to react to a stressors in
a presumably noxious fashion. Typically, we donxt know whether the str
ess reactivity pattern is harmful in a long term perspective, on a day
basic. Thus stress reactivity scientists would need help from and int
eraction with epidemiologists and social scientists to determine how m
uch impact this pathogenic mechanism could possibly have on the occurr
ence of disease in the population. Another new perspective is created
by the introduction of the concept of interaction into theory on causa
tion. E.g. the potential to understand psychosocial or psychosomatic d
isease processes has greatly increased by the simple paradigm of consi
dering the effects of stressors of the social environment in the conte
xt of specific personality characteristics. One such example is the st
rain of social isolation, which seems to be considerably stronger in i
ndividuals with a specific set of characteristics, the so-called Type
a Behavior, than in individuals without such behavior, Type B individu
als. This interactive model helps to explain some of the inconsistenci
es in findings from various studies of personality and behavior type p
atterns. Last but not least we have improved our possibilities and pot
entiated our perspectives by the rapid increase in interaction across
nations. Comparisons across cultures will greatly enhance the possibil
ities to understand disease processes, once they are systematically an
d objectively performed. All these options for interactive efforts pro
mise to underscore the role of this field of research, which deals wit
h the interface between body and mind. In that context I believe it is
unimportant whether we call it psychosocial medicine, behavioral medi
cine or psychosomatic medicine. The importance lies in the fact that w
e need to strengthen our efforts to interact on a theoretical level, o
n a practical level, on a methodological level and on a personal level
.