Purpose: A retrospective review of 124 patients who underwent carotid-
subclavian bypass from 1968 to 1990 was done to assess primary patency
and symptom resolution. Methods: Preoperative data included age, athe
rosclerosis risk factors, and indications for surgery. Perioperative d
ata included mortality and morbidity rates and graft conduit. Postoper
ative follow-up assessed graft patency, resolution of symptoms, and la
te survival. Results: Age ranged from 42 to 78 years (mean 57.9). Indi
cations for surgery were vertebrobasilar insufficiency in 24 (19%), ex
tremity ischemia (EI) in 33 (27%), transient ischemic attacks (TIAs) i
n 13 (11%), both vertebrobasilar insufficiency and EI in 31 (25%), and
both TLAs and EI in 23 (18%) patients. Graft conduits were polytetraf
luoroethylene in 44 (35%) and Dacron in 80 (65%) cases. Concomitant ip
silateral carotid endarterectomy was done in 32 (26%) patients. During
operation, death occurred in one patient (0.8%), and complications oc
curred in 10 (8%) patients. Thirty-day primary patency and symptom-fre
e survival rates were 100%. Long-term follow-up ranging from 5 to 164
months was available for the 60 cases done between 1975 and 1990. Thre
e grafts occluded at 30, 36, and 51 months after surgery for a primary
patency rate of 95% at 5 and 10 years. Twenty-two patients died, yiel
ding survival rates of 83% at 5 years and 59% at 10 years. Symptom rec
urrence occurred in six (10%) patients from 9 to 66 months after surge
ry. The symptom-free survival rate was 98% at 1 year, 90% at 5 years,
and 87% gt 10 years. Symptoms recurred in three patients with occluded
grafts and three with patent grafts. The preoperative symptoms of dro
p attacks and TIAs did not recur. EI recurred in 5% and was noted only
in the presence of graft occlusion. Dizziness recurred in 17% of pati
ents admitted with this symptom and was observed despite graft patency
. Conclusion: Carotid-subclavian bypass was a safe and durable procedu
re for relief of symptomatic occlusive disease of the subclavian arter
y. Long-term symptomatic relief appeared particularly likely in patien
ts with drop attacks or upper extremity ischemia.