Quercetin (Que) ig 200 mg.kg(-1), qd X 14 d decreased activities of th
e Na-(+)-K-(+)-exchanging ATPase (I) of rat brain plasma membranes and
heart sarcolemmal and Ca-(2+) Mg-(2+)-ATPase (II) of heart sarcolemma
l membrane. Que 100 mg.kg(-1) reduced the activity of I from rat heart
sarcolemmal prepartion, but had no effect on that from rat brain plas
ma membranes. The result shows that I of myodardium is more senstive t
han that of brain in rat. Que also showed a remarkable inhibitory effe
ct in the II of heart sarcolemma.