EFFECTS OF QUERCETIN ON NA(-K(+)-EXCHANGING ATPASE AND CA(2+) MG(2+)-ATPASE IN RATS())

Citation
Zl. Gu et al., EFFECTS OF QUERCETIN ON NA(-K(+)-EXCHANGING ATPASE AND CA(2+) MG(2+)-ATPASE IN RATS()), Zhongguo yaoli xuebao, 15(5), 1994, pp. 414-416
Citations number
13
Categorie Soggetti
Pharmacology & Pharmacy",Chemistry
Journal title
ISSN journal
02539756
Volume
15
Issue
5
Year of publication
1994
Pages
414 - 416
Database
ISI
SICI code
0253-9756(1994)15:5<414:EOQONA>2.0.ZU;2-D
Abstract
Quercetin (Que) ig 200 mg.kg(-1), qd X 14 d decreased activities of th e Na-(+)-K-(+)-exchanging ATPase (I) of rat brain plasma membranes and heart sarcolemmal and Ca-(2+) Mg-(2+)-ATPase (II) of heart sarcolemma l membrane. Que 100 mg.kg(-1) reduced the activity of I from rat heart sarcolemmal prepartion, but had no effect on that from rat brain plas ma membranes. The result shows that I of myodardium is more senstive t han that of brain in rat. Que also showed a remarkable inhibitory effe ct in the II of heart sarcolemma.