SPATIAL-ASPECTS OF HUMAN BLOOD-CLOTTING D YNAMICS .1. HYPOTHESIS

General physical requirements concerning spacial development of a thro mb as well as modern biochemical kinetic data on blood coagulation sys tem have been analized. The hypothesis assuming an autowave mechanism of blood clotting process is proposed. It is suggested that the thromb in autowave propagates in blood starting from the site of vessel injur y. Behind the front of this wave the conditions necessary for appearan ce of the anticoagulation autowave (which inhibits the clotting proces s) are being created. The second wave starts later and propagates with greater speed catching up the first one at the definite distance; the clotting process is stoped al this moment. The crucial experiment to verify the hypothesis is proposed.