It is usually accepted that the phenomenon of thick filament shortenin
g contradicts the sliding filament theory and cross-bridge mechanism o
f force generation. However, some peculiarity of experimental data ind
icate that thick filament shortening can be a corollary of the. intera
ction of myosin cross-bridges with the actin filaments <<wrong>> polar
ities in sarcomeres with the actin filaments double overlap formed in
the results of the filament sliding.