Examination of knee menisci of Bengal tigers revealed ossicles within
the cartilaginous anterior horn of each medial meniscus. This ossifica
tion was not evident in the neonatal animal, but was present in animal
s aged 20 months or older. The ossicle appeared prior to the completio
n of skeletal maturation at the knee, and was composed of normal remod
eling trabecular bone. While most animals had a single, variably sized
ossicle, multiple ossicles also occurred. The meniscal cartilage appo
sed to the femoral articulation exhibited a distinct columnar pattern
in the region of the ossicle, in contrast to the non-columnar pattern
throughout the bulk of the meniscus, including the ossicle side appose
d to the tibial plateau. In this particular large mammalian species me
dial meniscal ossification appears to be a normal anatomical variation
that progressively develops following birth, and may serve as a model
for the phylogenetic (developmental) theory of etiology.