HEADACHE AND COGNITIVE DYSFUNCTIONS IN SNORERS - A CROSS-SECTIONAL STUDY OF 3323 MEN AGED 54 TO 74 YEARS - THE COPENHAGEN MALE STUDY

Objective: Cognitive symptoms, headache, and sleep-related complaints, including snoring, are commonly reported by patients with sleep apnea . Because patients with sleep apnea generally are snorers, we decided to study whether snoring per se is associated with cognitive complaint s and headache. Design: Cross-sectional epidemiologic follow-up study. Setting: General community. Participants: A total of 3323 men, aged 5 4 to 74 years, previously selected from among employees of public or p rivate companies in the Copenhagen, Denmark, area. Method: Participant s were classified according to self-reported snoring habits and these were compared with self-reported cognitive complaints and headache. Fo urteen potential confounders were included. Results: The odds ratio (9 5% confidence interval) for headache was 1.5 (1.3 to 1.8, P<.0001) for self-reported snorers after adjustments for age, body mass index, and alcohol and tobacco consumption, whereas no relationships were found between snoring and memory or concentration problems in the total popu lation. Snoring was not related to use of central nervous system medic ation; previous stroke; presence of parkinsonism, epilepsy, or psychia tric diseases; previous head trauma; or exposure to organic solvents. Hypersomnia was significantly associated with snoring (P<.0001), heada che (P<.0001), memory problems (P<.0001), concentration problems (P<.0 001), age (P<.01), body mass index (P<.001), and alcohol consumption ( P<.05) and negatively correlated with smoking (P<.0001). Irrespective of the severity of hypersomnia, no association was found between snori ng and memory or concentration problems. The relationship between snor ing and headache was independent of severity of hypersomnia. Conclusio ns: Snoring is associated with headache but not with cognitive dysfunc tion. Hypersomnia shows a correlation to cognitive problems. If associ ations are found between snoring and cognitive dysfunction, these may be related in part to the presence of hypersomnia.