CLINICAL, RADIOLOGICAL AND HISTOLOGICAL-FINDINGS IN DESMOPLASTIC INFANTILE GANGLIOGLIOMA

The clinical course and radiological and histological findings in a 30 -month-old boy suffering from desmoplastic infantile ganglioglioma are reported. The child's development was normal until a series of comple x partial seizures occurred at the age of 7 months. Cranial computed t omography and magnetic resonance imaging revealed a cystic mass with i ntensive ring-shaped contrast enhancement in the right temporal fossa without shift of intracranial structures. Histologically, the firm, gr ayish tumor showed an enormous amount of connective tissue, cystic are as, and some mitoses. Glial and neuronal cell lines were identified by immunocytochemical methods. Eighteen months after surgery the boy had developed well without any neurological dysfunction; no radiation or chemotherapy was given. For the first time a synopsis of radiological findings in this rare brain tumor is correlated with the results of mu ltiple histological and immunocytochemical studies. Despite some malig nant characteristics, the prognosis of this dysontogenetic brain tumor is good.